Blar i forfatter "Hirsch, Hans H."

Viser treff 1-3 av 3

    • BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and promotes mitophagy 

      Manzetti, Julia; Weissbach, Fabian H.; Graf, Fabrice E.; Unterstab, Gunhild; Wernli, Marion; Hopfer, Helmut; Drachenberg, Cinthia B.; Rinaldo, Christine Hanssen; Hirsch, Hans H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-10)
      Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients. Despite virus-specific T cells and neutralizing antibodies, BKPyV persists in kidneys and evades immune control as evidenced by urinary shedding in immunocompetent individuals. ...

    • Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta 

      Simon-Santamaria, Jaione; Rinaldo, Christine Hanssen; Kardas, Piotr; Li, Ruomei; Malovic, Ivana; Elvevold, Kjetil H.; McCourt, Peter Anthony; Smedsrød, Bård; Hirsch, Hans H.; Sørensen, Karen Kristine (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-06)

    • Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study 

      Olsøy, Irene Beate; Henriksen, Stian; Weissbach, Fabian H.; Larsen, Marthe; Borgen, Karoline; Abravanel, Florence; Kamar, Nassim; Paulssen, Eyvind Jakob; Hirsch, Hans H.; Rinaldo, Christine Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-22)
      Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in many parts of the world but only a few cases have been diagnosed in Norway. To investigate the HEV exposure rate in a presumed low-risk area, we have conducted a population-based study of anti-HEV IgG seroprevalence in Northern Norway. A total of 1800 serum samples from 900 women and 900 men, age 40–79 years, were randomly selected ...